Ausgewählte Publikationen

Binkle L, Klein M, Borgmeyer U, Kuhl D, Hermey G.
The adaptor protein PICK1 targets the sorting receptor SorLA
Mol Brain. 2022 Feb 19;15(1):18.

Klein M, Kaleem A, Oetjen S, Wünkhaus D, Binkle L, Schilling S, Gjorgjieva M, Scholz R, Gruber-Schoffnegger D, Storch S, Kins S, Drewes G, Hoffmeister-Ullerich S, Kuhl D, Hermey G.
Converging roles of PSENEN/PEN2 and CLN3 in the autophagy-lysosome system.
Autophagy. 2021 Dec 29;1-18. Online ahead of print

Denkena J, Zaisser A, Merz B, Klinger B, Kuhl D, Blüthgen N, Hermey G.
Neuronal activity regulates alternative exon usage.
Mol Brain. 2020 Nov 10;13(1):148.

Schob C, Morellini F, Ohana O, Bakota L, Hrynchak MV, Brandt R, Brockmann MD, Cichon N, Hartung H, Hanganu-Opatz IL, Kraus V, Scharf S, Herrmans-Borgmeyer I, Schweizer M, Kuhl D, Wöhr M, Vörckel KJ, Calzada-Wack J, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Garner CC, Kreienkamp HJ, Kindler S.
Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice.
Transl Psychiatry. 2019 Jan 16;9(1):7. doi: 10.1038/s41398-018-0327-z.

Hermey G, Hoffmeister-Ullerich SA, Merz B, Groß D, Kuhl D, Kins S.
Amyloidosis causes downregulation of SorLA, SorCS1 and SorCS3 expression in mice.
Biol Chem. 2019 Aug 27;400(9):1181-1189. doi: 10.1515/hsz-2019-0146.

Gao X, Grendel J, Muhia M, Castro-Gomez S, Süsens U, Isbrandt D, Kneussel M, Kuhl D, Ohana O.
Disturbed Prefrontal Cortex Activity in the Absence of Schizophrenia-Like Behavioral Dysfunction in Arc/Arg3.1 Deficient Mice.J Neurosci. 2019 Oct 9;39(41):8149-8163.
J Neurosci. 2019 Oct 9;39(41):8149-8163.

Gao X, Castro-Gomez S, Grendel J, Graf S, Susens U, Binkle L, Mensching D, Isbrandt D, Kuhl D*, Ohana O* (2018) Arc/Arg3.1 mediates a critical period for spatial learning and hippocampal networks. Proc Natl Acad Sci USA (PNAS) 115:12531-12536. *corresponding authors

Hermey G, Mahlke C, Gutzmann JJ, Schreiber J, Blüthgen N, Kuhl D (2013) Genome-Wide Profiling of the Activity-Dependent Hippocampal Transcriptome. PLoS ONE 8:e76903

Plath N, Ohana O, Dammermann B, Errington ML, Schmitz D, Gross C, Mao XS, Engelsberg A, Mahlke C, Weizl H, Kobaz U, Stawrakakis A, Fernandez E, Waltereit R, Bick-Sander A, Therstappen E, Cooke SF, Blanquet V, Wurst W, Salmen B, Boesl MR, Lipp HP, Grant SGN, Bliss TVP, Wolfer DP, Kuhl D (2006) Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories. Neuron 52:437-444

Wulff P, Vallon V, Huang DY, Volkl H, Yu F, Richter K, Jansen M, Schlunz M, Klingel K, Loffing J, Kauselmann G, Bosl MR, Lang F, Kuhl D (2002) Impaired renal Na+ retention in the sgk1-knockout mouse. J Clin Invest 110:1263-1268

Waltereit R, Dammermann B, Wulff P, Scafidi J, Staubli U, Kauselmann G, Bundman M, Kuhl D (2001) Arg3.1/Arc mRNA induction by Ca2+ and cAMP requires protein kinase A and mitogen-activated protein kinase/extracellular regulated kinase activation. J Neurosci 21:5484-5493

Konietzko U, Kauselmann G, Scafidi J, Staubli U, Mikkers H, Berns A, Schweizer M, Waltereit R, Kuhl D (1999) Pim kinase expression is induced by LTP stimulation and required for the consolidation of enduring LTP. EMBO J 18:3359-3369

Kauselmann G, Weiler M, Wulff P, Jessberger S, Konietzko U, Scafidi J, Staubli U, Bereiter-Hahn J, Strebhardt K, Kuhl D (1999) The polo-like protein kinases Fnk and Snk associate with a Ca2+- and integrin-binding protein and are regulated dynamically with synaptic plasticity. EMBO J 18:5528-5539

Putz U, Skehel P, Kuhl D (1996) A tri-hybrid system for the analysis and detection of RNA-protein interactions. Nucleic Acids Res 24:4838-4840

Link W, Konietzko U, Kauselmann G, Krug M, Schwanke B, Frey U, Kuhl D (1995) Somatodendritic expression of an immediate early gene is regulated by synaptic activity. Proc Natl Acad Sci USA 92:5734-5738

Qian Z, Gilbert ME, Colicos MA, Kandel ER, Kuhl D (1993) Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation. Nature 361:453-457

Kuhl D, Kennedy TE, Barzilai A, Kandel ER (1992) Long-term sensitization training in Aplysia leads to an increase in the expression of BiP, the major protein chaperon of the ER. J Cell Biol 119:1069-1076

Kuhl D, Delafuente J, Chaturvedi M, Parimoo S, Ryals J, Meyer F, Weissmann C (1987) Reversible silencing of enhancers by sequences derived from the human IFN-alpha promoter. Cell 50:1057-1069

Publikationen Dietmar Kuhl