Martin Aepfelbacher
Prof. Dr. med.
Martin Aepfelbacher
  • Director of the institute
  • Deputy Director of Center
  • Medical specialist in Microbiology, Virology and Infectious Disease Epidemiology
Working area

Languages
German (Mother tongue)
English

Areas of expertise

Curriculum vitae

Publications

Zurück
  • 2024
  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2011
  • 2010
  • 2009
  • 2008
  • 2007
  • 2006
Vor

Adaptation and validation of a quantitative vanA/vanB DNA screening assay on a high-throughput PCR system
Giersch K, Tanida K, Both A, Nörz D, Heim D, Rohde H, Aepfelbacher M, Lütgehetmann M
SCI REP-UK. 2024;14(1):3523.

Analytical and clinical validation of a multiplex PCR assay for detection of Neisseria gonorrhoeae and Chlamydia trachomatis including simultaneous LGV serotyping on an automated high-throughput PCR system
Pflüger L, Nörz D, Grunwald M, Pfefferle S, Giersch K, Christner M, Weber B, Aepfelbacher M, Rohde H, Lütgehetmann M
MICROBIOL SPECTR. 2024;12(3):e0275623.

Evaluation of a rapid combination disc test (RCDT) for direct phenotypic detection of extended-spectrum β-lactamase production in E. coli from positive blood culture bottles
Berinson B, Degel-Brossmann N, Olearo F, Roggenkamp H, Both A, Aepfelbacher M, Christner M, Rohde H
J ANTIMICROB CHEMOTH. 2023;78(4):1028-1033.

Performance and Hypothetical Impact on Joint Infection Management of the BioFire Joint Infection Panel: a Retrospective Analysis
Berinson B, Spenke L, Krivec L, Tanida K, Both A, Keller J, Rolvien T, Christner M, Lütgehetmann M, Aepfelbacher M, Klatte T, Rohde H
J CLIN MICROBIOL. 2023;61(8):.

A bacterial effector protein promotes nuclear translocation of Stat3 to induce IL-10.
Berneking L, Bekere I, Rob S, Schnapp M, Huang J, Ruckdeschel K, Aepfelbacher M
EUR J CELL BIOL. 2023;102(4):151364.

Complete genome sequence of a Staphylococcus condimenti isolated from a port catheter-associated bloodstream infection
Berneking L, Büttner H, Qi M, Günther T, Lehnhoff D, Both A, Christner M, Wolters M, Alawi M, Aepfelbacher M, Rohde H
MICROBIOL RESOUR ANN. 2023;12(10):.

The added value of a commercial 16S/18S-PCR assay (UMD-SelectNA, Molzym) for microbiological diagnosis of spondylodiscitis:an observational study
Both A, Christner M, Berinson B, Dreimann M, Viezens L, Lütgehetmann M, Aepfelbacher M, Rohde H, Stangenberg M
DIAGN MICR INFEC DIS. 2023;106(1):.

Genomics of Invasive Cutibacterium acnes Isolates from Deep-Seated Infections
Both A, Huang J, Hentschke M, Tobys D, Christner M, Klatte T, Seifert H, Aepfelbacher M, Rohde H
MICROBIOL SPECTR. 2023;11(2):e0474022.

First case of bloodstream infection caused by Mixta hanseatica sp. nov., a novel species within the Mixta genus of the Erwiniaceae family
Both A, Huang J, Wenzel P, Aepfelbacher M, Rohde H, Christner M, Hentschke M
NEW MICROB NEW INFEC. 2023;53:101117.

Rapid Development of cefiderocol resistance in a carbapenem-resistant Pseudomonas aeruginosa isolate associated with mutations in the pyoverdine biosynthesis pathway
Brakert L, Berneking L, Both A, Berinson B, Huang J, Aepfelbacher M, Wolschke C, Wichmann D, Rohde H
J GLOB ANTIMICROB RE. 2023;34:59-62.

MINFLUX imaging of a bacterial molecular machine at nanometer resolution
Carsten A, Rudolph M, Weihs T, Schmidt R, Jansen I, Wurm C, Diepold A, Failla A, Wolters M, Aepfelbacher M
METHODS APPL FLUORES. 2023;11(1):.

Super-resolution fluorescence microscopy for investigating bacterial cell biology
Carsten A, Wolters M, Aepfelbacher M
MOL MICROBIOL. 2023 [Epub ahead of print].

Integration of Sequencing and Epidemiologic Data for Surveillance of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infections in a Tertiary-Care Hospital
Czech-Sioli M, Günther T, Robitaille A, Roggenkamp H, Büttner H, Indenbirken D, Christner M, Lütgehetmann M, Knobloch J, Aepfelbacher M, Grundhoff A, Fischer N
CLIN INFECT DIS. 2023;76(3):e263-e273.

Epidemiology of co-infections in pregnant women living with human immunodeficiency virus 1 in rural Gabon: a cross-sectional study
Davi S, Okwu D, Luetgehetmann M, Abba F, Aepfelbacher M, Endamne L, Alabi A, Zoleko-Manego R, Mombo-Ngoma G, Mahmoudou S, Addo M, Ramharter M, Mischlinger J
INFECT DIS POVERTY. 2023;12(1):.

Performance of an interferon-γ release assay-based test for cell-mediated immunity to SARS-CoV-2
Fonseca B, Tödter S, Kottlau J, Cermann K, Spier A, Petersen E, Schäfer I, Twerenbold R, Aepfelbacher M, Lütgehetmann M, Stahl F
FRONT IMMUNOL. 2023;14:1069968.

New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany
Heinrich F, Huter T, Mertens S, Lange P, Vering J, Heinemann A, Nörz D, Hoffmann A, Aepfelbacher M, Ondruschka B, Krasemann S, Lütgehetmann M
EMERG INFECT DIS. 2023;29(3):652-656.

Tecovirimat therapy for severe monkeypox infection: Longitudinal assessment of viral titers and clinical response pattern-A first case-series experience
Hermanussen L, Grewe I, Tang H, Nörz D, Bal L, Pfefferle S, Unger S, Hoffmann C, Berzow D, Kohsar M, Aepfelbacher M, Lohse A, Addo M, Lütgehetmann M, Schulze zur Wiesch J, Schmiedel S
J MED VIROL. 2023;95(1):e28181.

The Impact of Antimicrobial Therapy Duration in the Treatment of Prosthetic Joint Infections Depending on Surgical Strategies:A Systematic Review and Meta-analysis
Olearo F, Zanichelli V, Exarchakou A, Both A, Uςkay I, Aepfelbacher M, Rohde H
OPEN FORUM INFECT DI. 2023;10(5):.

Detection of human herpes virus 6 DNA and chromosomal integration after allogeneic hematopoietic stem cell transplantation: a retrospective single center analysis
Berneking L, Both A, Langebrake C, Aepfelbacher M, Lütgehetmann M, Kröger N, Christopeit M
TRANSPL INFECT DIS. 2022;24(3):e13836.

Evaluation of a syndromic panel polymerase chain reaction (spPCR) assay for the diagnosis of device associated bone and joint infections (BJI)
Berneking L, Haas M, Frielinghaus L, Berinson B, Lütgehetmann M, Christner M, Aepfelbacher M, Gerlach U, Seide K, Both A, Rohde H
INT J INFECT DIS. 2022;116:283-288.

Population dynamics in colonizing vancomycin-resistant Enterococcus faecium isolated from immunosuppressed patients
Both A, Kruse F, Mirwald N, Franke G, Christner M, Huang J, Hansen J, Kröger N, Berneking L, Lellek H, Aepfelbacher M, Rohde H
J GLOB ANTIMICROB RE. 2022;28:267-273.

Clinical efficacy and in vitro neutralization capacity of monoclonal antibodies for severe acute respiratory syndrome coronavirus 2 delta and omicron variants
Brehm T, Pfefferle S, von Possel R, Karolyi M, Zoufaly A, Wichmann D, Kobbe R, Emmerich P, Nörz D, Aepfelbacher M, Schulze Zur Wiesch J, Addo M, Schmiedel S, Lütgehetmann M
J MED VIROL. 2022;94(10):5038-5043.

Three Separate Spike Antigen Exposures by COVID-19 Vaccination or SARS-CoV-2 Infection Elicit Strong Humoral Immune Responses in Healthcare Workers
Brehm T, Ullrich F, Thompson M, Küchen J, Schwinge D, Spier A, Huber S, Knobloch J, Aepfelbacher M, Addo M, Lohse A, Lütgehetmann M, Schulze Zur Wiesch J
VACCINES-BASEL. 2022;10(7):.

Detection of SARS-CoV-2 genomic and subgenomic RNA in retina and optic nerve of patients with COVID-19
Casagrande M, Fitzek A, Spitzer M, Püschel K, Glatzel M, Krasemann S, Aepfelbacher M, Nörz D, Lütgehetmann M, Pfefferle S, Spitzer M
BRIT J OPHTHALMOL. 2022;106(9):1313-1317.

Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2-Associated Deaths
Heinrich F, Schröder A, Gerberding A, Gerling M, Langenwalder F, Lange P, Heinemann A, Bibiza-Freiwald E, Nörz D, Aepfelbacher M, Pfefferle S, Ondruschka B, Lütgehetmann M
EMERG INFECT DIS. 2022;28(1):244-247.

Remdesivir-induced emergence of SARS-CoV2 variants in patients with prolonged infection
Heyer A, Günther T, Robitaille A, Lütgehetmann M, Addo M, Jarczak D, Kluge S, Aepfelbacher M, Schulze Zur Wiesch J, Fischer N, Grundhoff A
CELL REP MED. 2022;3(9):.

Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?
Jonigk D, Werlein C, Acker T, Aepfelbacher M, Amann K, Baretton G, Barth P, Bohle R, Büttner A, Büttner R, Dettmeyer R, Eichhorn P, Elezkurtaj S, Esposito I, Evert K, Evert M, Fend F, Gaßler N, Gattenlöhner S, Glatzel M, Göbel H, Gradhand E, Hansen T, Hartmann A, Heinemann A, Heppner F, Hilsenbeck J, Horst D, Kamp J, Mall G, Märkl B, Ondruschka B, Pablik J, Pfefferle S, Quaas A, Radbruch H, Röcken C, Rosenwald A, Roth W, Rudelius M, Schirmacher P, Slotta-Huspenina J, Smith K, Sommer L, Stock K, Ströbel P, Strobl S, Titze U, Weirich G, Weis J, Werner M, Wickenhauser C, Wiech T, Wild P, Welte T, von Stillfried S, Boor P
VIRCHOWS ARCH. 2022;481(2):139-159.

Infectivity of SARS-CoV-2 on Inanimate Surfaces: Don't Trust Ct Value
Knobloch J, Pfefferle S, Lütgehetmann M, Nörz D, Klupp E, Belmar Campos C, Kluge S, Aepfelbacher M, Knobling B, Franke G
INT J ENV RES PUB HE. 2022;19(24):.

Comparing susceptibility and contagiousness in concurrent outbreaks with a non-VOC and the VOC SARS-CoV-2 variant B.1.1.7 in daycare centers in Hamburg, Germany
Nakel J, Robitaille A, Günther T, Rosenau L, Czech-Sioli M, Plenge-Bönig A, Bühler S, Wille A, Jakubowski E, Pruskil S, Wahlen M, Indenbirken D, Nörz D, Lütgehetmann M, Aepfelbacher M, Grundhoff A, Grolle B, Fischer N
INT J HYG ENVIR HEAL. 2022;240:.

Clinical characteristics and comparison of longitudinal qPCR results from different specimen types in a cohort of ambulatory and hospitalized patients infected with monkeypox virus
Nörz D, Brehm T, Tang H, Grewe I, Hermanussen L, Matthews H, Pestel J, Degen O, Günther T, Grundhoff A, Fischer N, Addo M, Jordan S, Hertling S, Unger S, Schäfer G, Schewe K, Hoffmann C, Aepfelbacher M, Pfefferle S, Schulze Zur Wiesch J, Schmiedel S, Lütgehetmann M
J CLIN VIROL. 2022;155:.

Clinical Evaluation of a Fully-Automated High-Throughput Multiplex Screening-Assay to Detect and Differentiate the SARS-CoV-2 B.1.1.529 (Omicron) and B.1.617.2 (Delta) Lineage Variants
Nörz D, Grunwald M, Tang H, Weinschenk C, Günther T, Robitaille A, Giersch K, Fischer N, Grundhoff A, Aepfelbacher M, Pfefferle S, Lütgehetmann M
VIRUSES-BASEL. 2022;14(3):.

Evidence of surface contamination in hospital rooms occupied by patients infected with monkeypox, Germany, June 2022
Nörz D, Pfefferle S, Brehm T, Franke G, Grewe I, Knobling B, Aepfelbacher M, Huber S, Klupp E, Jordan S, Addo M, Schulze Zur Wiesch J, Schmiedel S, Lütgehetmann M, Knobloch J
EUROSURVEILLANCE. 2022;27(26):.

Rapid Adaptation of Established High-Throughput Molecular Testing Infrastructure for Monkeypox Virus Detection
Nörz D, Tang H, Emmerich P, Giersch K, Fischer N, Schmiedel S, Addo M, Aepfelbacher M, Pfefferle S, Lütgehetmann M
EMERG INFECT DIS. 2022;28(9):1765-1769.

Anti-SARS-CoV-2 antibodies in breast milk during lactation after infection or vaccination: A cohort study
Olearo F, Radmanesh L, Felber N, von Possel R, Emmerich P, Pekarek N, Pfefferle S, Nörz D, Hansen G, Diemert A, Aepfelbacher M, Hecher K, Lütgehetmann M, Arck P, Tallarek A
J REPROD IMMUNOL. 2022;153:.

C25-modified rifamycin derivatives with improved activity against Mycobacterium abscessus
Paulowski L, Beckham K, Johansen M, Berneking L, Van N, Degefu Y, Staack S, Sotomayor F, Asar L, Rohde H, Aldridge B, Aepfelbacher M, Parret A, Wilmanns M, Kremer L, Combrink K, Maurer F
PNAS nexus. 2022;1(4):.

Structural basis to repurpose boron-based proteasome inhibitors Bortezomib and Ixazomib as β-lactamase inhibitors
Perbandt M, Werner N, Prester A, Rohde H, Aepfelbacher M, Hinrichs W, Betzel C
SCI REP-UK. 2022;12(1):.

Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme
Petersen E, Goßling A, Adam G, Aepfelbacher M, Behrendt C, Cavus E, Cheng B, Fischer N, Gallinat J, Kühn S, Gerloff C, Koch-Gromus U, Härter M, Hanning U, Huber T, Kluge S, Knobloch J, Kuta P, Schmidt-Lauber C, Lütgehetmann M, Magnussen C, Mayer C, Muellerleile K, Münch J, Nägele F, Petersen M, Renné T, Riedl K, Rimmele D, Schäfer I, Schulz H, Tahir E, Waschki B, Wenzel J, Zeller T, Ziegler A, Thomalla G, Twerenbold R, Blankenberg S
EUR HEART J. 2022;43(11):1124-1137.

Live imaging of Yersinia translocon formation and immune recognition in host cells
Rudolph M, Carsten A, Kulnik S, Aepfelbacher M, Wolters M
PLOS PATHOG. 2022;18(5):.

Development of an artificial synovial fluid useful for studying Staphylococcus epidermidis joint infections
Stamm J, Weißelberg S, Both A, Failla A, Nordholt G, Büttner H, Linder S, Aepfelbacher M, Rohde H
FRONT CELL INFECT MI. 2022;12:.

First report from the German COVID-19 autopsy registry
von Stillfried S, Bülow R, Röhrig R, Boor P
LANCET REG HEALTH-EU. 2022;15:.

Intracranial hemorrhage in COVID-19 patients during extracorporeal membrane oxygenation for acute respiratory failure: a nationwide register study report
von Stillfried S, Bülow R, Röhrig R, Meybohm P, Boor P
CRIT CARE. 2022;26(1):.

Update zur kooperativen autopsiebasierten Forschung in der deutschen Pathologie, Neuropathologie und Gerichtsmedizin
von Stillfried S, Freeborn B, Windeck S, Boor P
PATHOLOGIE. 2022;43(Suppl 1):101-105.

Molecular consequences of SARS-CoV-2 liver tropism
Wanner N, Andrieux G, Badia-I-Mompel P, Edler C, Pfefferle S, Lindenmeyer M, Schmidt-Lauber C, Czogalla J, Wong M, Okabayashi Y, Braun F, Lütgehetmann M, Meister E, Lu S, Noriega M, Günther T, Grundhoff A, Fischer N, Bräuninger H, Lindner D, Westermann D, Haas F, Roedl K, Kluge S, Addo M, Huber S, Lohse A, Reiser J, Ondruschka B, Sperhake J, Saez-Rodriguez J, Boerries M, Hayek S, Aepfelbacher M, Scaturro P, Puelles V, Huber T
NAT METAB. 2022;4(3):310-319.

Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive
Zielinski K, Prester A, Andaleeb H, Bui S, Yefanov O, Catapano L, Henkel A, Wiedorn M, Lorbeer O, Crosas E, Meyer J, Mariani V, Domaracky M, White T, Fleckenstein H, Sarrou I, Werner N, Betzel C, Rohde H, Aepfelbacher M, Chapman H, Perbandt M, Steiner R, Oberthuer D
IUCRJ. 2022;9(Pt 6):778-791.

Yersinia remodels epigenetic histone modifications in human macrophages
Bekere I, Huang J, Schnapp M, Rudolph M, Berneking L, Ruckdeschel K, Grundhoff A, Günther T, Fischer N, Aepfelbacher M
PLOS PATHOG. 2021;17(11):.

Usefulness of Biofire FilmArray BCID2 for blood culture processing in clinical practice
Berinson B, Both A, Berneking L, Christner M, Lütgehetmann M, Aepfelbacher M, Rohde H
J CLIN MICROBIOL. 2021;59(8):e0054321.

EUCAST rapid antimicrobial susceptibility testing (RAST): analytical performance and impact on patient management
Berinson B, Olearo F, Both A, Brossmann N, Christner M, Aepfelbacher M, Rohde H
J ANTIMICROB CHEMOTH. 2021;76(5):1332-1338.

Performance of a loop-mediated isothermal amplification assay (Isoplex CRE-ART) to detect common carbapenemase-encoding genes in Gram-negative bacteria
Berneking L, Asar L, Both A, Berinson B, Aepfelbacher M, Lütgehetmann M, Rohde H
J MED MICROBIOL. 2021;70(7):.

Performance of the BD Phoenix CPO detect assay for detection and classification of carbapenemase-producing organisms
Berneking L, Both A, Berinson B, Hoffmann A, Lütgehetmann M, Aepfelbacher M, Rohde H
EUR J CLIN MICROBIOL. 2021;40(5):979-985.

Distinct clonal lineages and within-host diversification shape invasive Staphylococcus epidermidis populations
Both A, Huang J, Qi M, Lausmann C, Weißelberg S, Büttner H, Lezius S, Failla A, Christner M, Stegger M, Gehrke T, Baig S, Citak M, Alawi M, Aepfelbacher M, Rohde H
PLOS PATHOG. 2021;17(2):e1009304.

Heatwave-associated Vibrio infections in Germany, 2018 and 2019
Brehm T, Berneking L, Sena Martins M, Dupke S, Jacob D, Drechsel O, Bohnert J, Becker K, Kramer A, Christner M, Aepfelbacher M, Schmiedel S, Rohde H
EUROSURVEILLANCE. 2021;26(41):2002041.

SARS-CoV-2 Reinfection in a Healthcare Worker Despite the Presence of Detectable Neutralizing Antibodies
Brehm T, Pfefferle S, von Possel R, Kobbe R, Nörz D, Schmiedel S, Grundhoff A, Olearo F, Emmerich P, Robitaille A, Günther T, Braun P, Andersen G, Knobloch J, Addo M, Lohse A, Aepfelbacher M, Fischer N, Schulze Zur Wiesch J, Lütgehetmann M
VIRUSES-BASEL. 2021;13(4):.

Low SARS-CoV-2 infection rates and high vaccine-induced immunity among German healthcare workers at the end of the third wave of the COVID-19 pandemic
Brehm T, Thompson M, Ullrich F, Schwinge D, Addo M, Spier A, Knobloch J, Aepfelbacher M, Lohse A, Lütgehetmann M, Schulze Zur Wiesch J
INT J HYG ENVIR HEAL. 2021;238:.

Intestinal Colonization with Tropheryma whipplei—Clinical and Immunological Implications for HIV Positive Adults in Ghana
Eberhardt K, Sarfo F, Klupp E, Dompreh A, Cristanziano V, Kuffour E, Boateng R, Norman B, Phillips R, Aepfelbacher M, Feldt T
MICROORGANISMS. 2021;9(8):1781.

Prospective postmortem evaluation of 735 consecutive SARS-CoV-2-associated death cases
Fitzek A, Schädler J, Dietz E, Ron A, Gerling M, Kammal A, Lohner L, Falck C, Möbius D, Goebels H, Gerberding A, Schröder A, Sperhake J, Klein A, Fröb D, Mushumba H, Wilmes S, Anders S, Kniep I, Heinrich F, Langenwalder F, Meißner K, Lange P, Zapf A, Püschel K, Heinemann A, Glatzel M, Matschke J, Aepfelbacher M, Lütgehetmann M, Steurer S, Thorns C, Edler C, Ondruschka B
SCI REP-UK. 2021;11(1):19342.

Clinical evaluation of a laboratory-developed quantitative BK virus-PCR assay using the cobas® omni Utility Channel
Fritzsche A, Berneking L, Nörz D, Reucher S, Fischer N, Roggenkamp H, Aepfelbacher M, Rohde H, Pfefferle S, Lütgehetmann M
J VIROL METHODS. 2021;290:114093.

Polymicrobial enteric infections in african infants with diarrhoea - Results from a longitudinal prospective case-control study
Heinemann M, Strauchs C, Lütgehetmann M, Aepfelbacher M, Klupp E, Owusu-Dabo E, Rolling T, Cramer J, Vinnemeier C
CLIN MICROBIOL INFEC. 2021;27(12):1792-1798.

Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa
Heinrich F, Meißner K, Langenwalder F, Püschel K, Hoffmann A, Lütgehetmann M, Aepfelbacher M, Bibiza-Freiwald E, Pfefferle S, Heinemann A
EMERG INFECT DIS. 2021;27(1):329-331.

SARS-CoV-2 Blood RNA Load Predicts Outcome in Critically Ill COVID-19 Patients
Heinrich F, Nentwich M, Bibiza-Freiwald E, Nörz D, Roedl K, Christner M, Hoffmann A, Olearo F, Kluge S, Aepfelbacher M, Wichmann D, Lütgehetmann M, Pfefferle S
OPEN FORUM INFECT DI. 2021;8(11):.

Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis
Moreno-Layseca P, Jäntti N, Godbole R, Sommer C, Jacquemet G, Al-Akhrass H, Conway J, Kronqvist P, Kallionpää R, Oliveira-Ferrer L, Cervero P, Linder S, Aepfelbacher M, Zauber H, Rae J, Parton R, Disanza A, Scita G, Mayor S, Selbach M, Veltel S, Ivaska J
NAT CELL BIOL. 2021;23(10):1073-1084.

Evaluation of a fully automated high-throughput SARS-CoV-2 multiplex qPCR assay with built-in screening functionality for del-HV69/70- and N501Y variants such as B.1.1.7
Nörz D, Grunwald M, Olearo F, Fischer N, Aepfelbacher M, Pfefferle S, Lütgehetmann M
J CLIN VIROL. 2021;141:.

Rapid Automated Screening for SARS-CoV-2 B.1.617 Lineage Variants (Delta/Kappa) through a Versatile Toolset of qPCR-Based SNP Detection
Nörz D, Grunwald M, Tang H, Olearo F, Günther T, Robitaille A, Fischer N, Grundhoff A, Aepfelbacher M, Pfefferle S, Lütgehetmann M
DIAGNOSTICS. 2021;11(10):.

Clinical evaluation of a fully automated, laboratory-developed multiplex RT-PCR assay integrating dual-target SARS-CoV-2 and influenza A/B detection on a high-throughput platform
Nörz D, Hoffmann A, Aepfelbacher M, Pfefferle S, Lütgehetmann M
J MED MICROBIOL. 2021;70(2):.

Modifying a Diagnostic SARS-CoV-2 Spike PCR to Turn a Del69/70 Dropout into a Discriminatory On-Target Assay
Nörz D, Pfefferle S, Grunwald M, Fischer N, Aepfelbacher M, Lütgehetmann M
J MOL DIAGN. 2021;23(6):777-778.

Emergence of linezolid-resistance in vancomycin-resistant Enterococcus faecium ST117 associated with increased linezolid-consumption
Olearo F, Both A, Belmar Campos C, Hilgarth H, Klupp E, Hansen J, Maurer F, Christner M, Aepfelbacher M, Rohde H
INT J MED MICROBIOL. 2021;311(2):.

Handling and accuracy of four rapid antigen tests for the diagnosis of SARS-CoV-2 compared to RT-qPCR
Olearo F, Nörz D, Heinrich F, Sutter J, Roedl K, Schultze A, Wiesch J, Braun P, Oestereich L, Kreuels B, Wichmann D, Aepfelbacher M, Pfefferle S, Lütgehetmann M
J CLIN VIROL. 2021;137:.

Clinical performance and accuracy of a qPCR-based SARS-CoV-2 mass-screening workflow for healthcare-worker surveillance using pooled self-sampled gargling solutions: a cross-sectional study
Olearo F, Nörz D, Hoffman A, Grunwald M, Gatzemeyer K, Christner M, Both A, Campos C, Braun P, Andersen G, Pfefferle S, Zapf A, Aepfelbacher M, Knobloch J, Lütgehetmann M
J INFECTION. 2021;83(5):589-593.

Multiorgan tropism of SARS-CoV-2 lineage B.1.1.7
Ondruschka B, Heinrich F, Lindenmeyer M, Edler C, Möbius D, Czogalla J, Heinemann A, Braun F, Aepfelbacher M, Lütgehetmann M, Huber T
INT J LEGAL MED. 2021;135(6):2347-2349.

SARS Coronavirus-2 variant tracing within the first Coronavirus Disease 19 clusters in northern Germany
Pfefferle S, Günther T, Kobbe R, Czech-Sioli M, Nörz D, Santer R, Oh J, Kluge S, Oestereich L, Peldschus K, Indenbirken D, Huang J, Grundhoff A, Aepfelbacher M, Knobloch J, Lütgehetmann M, Fischer N
CLIN MICROBIOL INFEC. 2021;27(1):130.e5-130.e8.

Viral Dynamics of SARS-CoV-2 in Critically Ill Allogeneic Hematopoietic Stem Cell Transplant Recipients and Immunocompetent Patients with COVID-19
Roedl K, Heidenreich S, Pfefferle S, Jarczak D, Urbanowicz T, Nörz D, Aepfelbacher M, Kröger N, Kluge S, Lütgehetmann M, Christopeit M, Wichmann D
AM J RESP CRIT CARE. 2021;203(2):242-245.

The handling of SARS-CoV-2 associated deaths - infectivity of the body
Schröder A, Edler C, Ondruschka B, Püschel K, Schädler J, Heinemann A, Heinrich F, Lütgehetmann M, Pfefferle S, Aepfelbacher M, Fitzek A, Sperhake J
FORENSIC SCI MED PAT. 2021;17(3):411-418.

Identification of Kosakonia cowanii as a rare cause of acute cholecystitis:case report and review of the literature
Berinson B, Bellon E, Christner M, Both A, Aepfelbacher M, Rohde H
BMC INFECT DIS. 2020;20(1):366.

Rapid identification of the vanA/vanB resistance determinant in Enterococcus sp. from blood cultures using the Cepheid Xpert vanA/vanB cartridge system
Both A, Berneking L, Berinson B, Lütgehetmann M, Christner M, Aepfelbacher M, Rohde H
DIAGN MICR INFEC DIS. 2020;96(4):114977.

SARS-CoV-2 renal tropism associates with acute kidney injury
Braun F, Lütgehetmann M, Pfefferle S, Wong M, Carsten A, Lindenmeyer M, Nörz D, Heinrich F, Meißner K, Wichmann D, Kluge S, Gross O, Pueschel K, Schröder A, Edler C, Aepfelbacher M, Puelles V, Huber T
LANCET. 2020;396(10251):597-598.

A Giant Extracellular Matrix Binding Protein of Staphylococcus epidermidis Binds Surface-Immobilized Fibronectin via a Novel Mechanism
Büttner H, Perbandt M, Kohler T, Kikhney A, Wolters M, Christner M, Heise M, Wilde J, Weißelberg S, Both A, Betzel C, Hammerschmidt S, Svergun D, Aepfelbacher M, Rohde H
MBIO. 2020;11(5):.

Correction to:Dying with SARS-CoV-2 infection-an autopsy study of the first consecutive 80 cases in Hamburg, Germany
Edler C, Schröder A, Aepfelbacher M, Fitzek A, Heinemann A, Heinrich F, Klein A, Langenwalder F, Lütgehetmann M, Meißner K, Püschel K, Schädler J, Steurer S, Mushumba H, Sperhake J
INT J LEGAL MED. 2020;134(5):1977.

Dying with SARS-CoV-2 infection-an autopsy study of the first consecutive 80 cases in Hamburg, Germany
Edler C, Schröder A, Aepfelbacher M, Fitzek A, Heinemann A, Heinrich F, Klein A, Langenwalder F, Lütgehetmann M, Meißner K, Püschel K, Schädler J, Steurer S, Mushumba H, Sperhake J
INT J LEGAL MED. 2020;134(4):1275-1284.

Der erste COVID-19-Hotspot in einer Hamburger Senioreneinrichtung: Präventionskonzept, Letalität und Obduktionsbefunde
Klein A, Edler C, Fitzek A, Fröb D, Heinemann A, Meißner K, Mushumba H, Püschel K, Schröder A, Sperhake J, Ishorst-Witte F, Aepfelbacher M, Heinrich F
RECHTSMEDIZIN. 2020;30(5):325-331.

Neuropathology of patients with COVID-19 in Germany: a post-mortem case series
Matschke J, Lütgehetmann M, Hagel C, Sperhake J, Schröder A, Edler C, Mushumba H, Fitzek A, Allweiss L, Dandri M, Dottermusch M, Heinemann A, Pfefferle S, Schwabenland M, Sumner Magruder D, Bonn S, Prinz M, Gerloff C, Püschel K, Krasemann S, Aepfelbacher M, Glatzel M
LANCET NEUROL. 2020;19(11):919-929.

Clinical evaluation of a SARS-CoV-2 RT-PCR assay on a fully automated system for rapid on-demand testing in the hospital setting
Nörz D, Fischer N, Schultze A, Kluge S, Mayer-Runge U, Aepfelbacher M, Pfefferle S, Lütgehetmann M
J CLIN VIROL. 2020;128:104390.

Pushing beyond specifications:Evaluation of linearity and clinical performance of the cobas 6800/8800 SARS-CoV-2 RT-PCR assay for reliable quantification in blood and other materials outside recommendations
Nörz D, Frontzek A, Eigner U, Oestereich L, Wichmann D, Kluge S, Fischer N, Aepfelbacher M, Pfefferle S, Lütgehetmann M
J CLIN VIROL. 2020;132:104650.

Implementation of the FilmArray ME panel in laboratory routine using a simple sample selection strategy for diagnosis of meningitis and encephalitis
Pfefferle S, Christner M, Aepfelbacher M, Lütgehetmann M, Rohde H
BMC INFECT DIS. 2020;20(1):170.

Complete Genome Sequence of a SARS-CoV-2 Strain Isolated in Northern Germany
Pfefferle S, Huang J, Nörz D, Indenbirken D, Lütgehetmann M, Oestereich L, Günther T, Grundhoff A, Aepfelbacher M, Fischer N
MICROBIOL RESOUR ANN. 2020;9(23):.

Clinical evaluation of five different automated SARS-CoV-2 serology assays in a cohort of hospitalized COVID-19 patients
Pflüger L, Bannasch J, Brehm T, Pfefferle S, Hoffmann A, Nörz D, van der Meirschen M, Kluge S, Haddad M, Pischke S, Hiller J, Addo M, Lohse A, Wiesch J, Peine S, Aepfelbacher M, Lütgehetmann M
J CLIN VIROL. 2020;130:104549.

Multiorgan and Renal Tropism of SARS-CoV-2
Puelles V, Lütgehetmann M, Lindenmeyer M, Sperhake J, Wong M, Allweiss L, Chilla S, Heinemann A, Wanner N, Liu S, Braun F, Lu S, Pfefferle S, Schröder A, Edler C, Gross O, Glatzel M, Wichmann D, Wiech T, Kluge S, Pueschel K, Aepfelbacher M, Huber T
NEW ENGL J MED. 2020;383(6):590-592.

Von den Toten lernen - neue Erkenntnisse zu Covid-19
Püschel K, Kluge S, Addo M, Aepfelbacher M
Hamb Ärztebl. 2020;73(06):34-36.

Autopsy Findings and Venous Thromboembolism in Patients With COVID-19: A Prospective Cohort Study
Wichmann D, Sperhake J, Lütgehetmann M, Steurer S, Edler C, Heinemann A, Heinrich F, Mushumba H, Kniep I, Schröder A, Burdelski C, de Heer G, Nierhaus A, Frings D, Pfefferle S, Becker H, Bredereke-Wiedling H, de Weerth A, Paschen H, Sheikhzadeh-Eggers S, Stang A, Schmiedel S, Bokemeyer C, Addo M, Aepfelbacher M, Püschel K, Kluge S
ANN INTERN MED. 2020;173(4):268-277.

DAMIAN an open source bioinformatics tool for fast, systematic and cohort based analysis of microorganisms in diagnostic samples
Alawi M, Burkhardt L, Indenbirken D, Reumann K, Christopeit M, Kröger N, Lütgehetmann M, Aepfelbacher M, Fischer N, Grundhoff A
SCI REP-UK. 2019;9(1):16841.

Influence of local epidemiology on the performance of common colistin drug susceptibility testing methods
Asar L, Pfefferle S, Lütgehetmann M, Hoffmann A, Katchanov J, Aepfelbacher M, Rohde H, Maurer F
PLOS ONE. 2019;14(6):e0217468.

Extended-spectrum β-lactamase-producing Enterobacteriaceae among geckos (Hemidactylus brookii) in a Ghanaian hospital
Eibach D, Nagel M, Lorenzen S, Hogan B, Belmar Campos C, Aepfelbacher M, Sarpong N, May J
CLIN MICROBIOL INFEC. 2019;25(8):1048-1050.

Nrf2 Sequesters Keap1 Preventing Podosome Disassembly:A Quintessential Duet Moonlights in Endothelium
Kloska D, Kopacz A, Cysewski D, Aepfelbacher M, Dulak J, Jozkowicz A, Grochot-Przeczek A
ANTIOXID REDOX SIGN. 2019;30(14):1709-1730.

Activation of the macroautophagy pathway by Yersinia enterocolitica promotes intracellular multiplication and egress of yersiniae from epithelial cells
Valencia Lopez M, Schimmeck H, Gropengießer J, Middendorf L, Quitmann M, Schneider C, Holstermann B, Wacker R, Heussler V, Reimer R, Aepfelbacher M, Ruckdeschel K
CELL MICROBIOL. 2019;21(9):e13046.

Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in local and imported poultry meat in Ghana
Eibach D, Dekker D, Gyau Boahen K, Wiafe Akenten C, Sarpong N, Belmar Campos C, Berneking L, Aepfelbacher M, Krumkamp R, Owusu-Dabo E, May J
VET MICROBIOL. 2018;217:7-12.

Visualization of translocons in Yersinia type III protein secretion machines during host cell infection
Nauth T, Huschka F, Schweizer M, Bosse J, Diepold A, Failla A, Steffen A, Stradal T, Wolters M, Aepfelbacher M
PLOS PATHOG. 2018;14(12):e1007527.

Megahertz serial crystallography
Wiedorn M, Oberthür D, Bean R, Schubert R, Werner N, Abbey B, Aepfelbacher M, Adriano L, Allahgholi A, Al-Qudami N, Andreasson J, Aplin S, Awel S, Ayyer K, Bajt S, Barák I, Bari S, Bielecki J, Botha S, Boukhelef D, Brehm W, Brockhauser S, Cheviakov I, Coleman M, Cruz-Mazo F, Danilevski C, Darmanin C, Doak R, Domaracky M, Dörner K, Du Y, Fangohr H, Fleckenstein H, Frank M, Fromme P, Gañán-Calvo A, Gevorkov Y, Giewekemeyer K, Ginn H, Graafsma H, Graceffa R, Greiffenberg D, Gumprecht L, Göttlicher P, Hajdu J, Hauf S, Heymann M, Holmes S, Horke D, Hunter M, Imlau S, Kaukher A, Kim Y, Klyuev A, Knoška J, Kobe B, Kuhn M, Kupitz C, Küpper J, Lahey-Rudolph J, Laurus T, Le Cong K, Letrun R, Xavier P, Maia L, Maia F, Mariani V, Messerschmidt M, Metz M, Mezza D, Michelat T, Mills G, Monteiro D, Morgan A, Mühlig K, Munke A, Münnich A, Nette J, Nugent K, Nuguid T, Orville A, Pandey S, Pena G, Villanueva-Perez P, Poehlsen J, Previtali G, Redecke L, Riekehr W, Rohde H, Round A, Safenreiter T, Sarrou I, Sato T, Schmidt M, Schmitt B, Schönherr R, Schulz J, Sellberg J, Seibert M, Seuring C, Shelby M, Shoeman R, Sikorski M, Silenzi A, Stan C, Shi X, Stern S, Sztuk-Dambietz J, Szuba J, Tolstikova A, Trebbin M, Trunk U, Vagovic P, Ve T, Weinhausen B, White T, Wrona K, Xu C, Yefanov O, Zatsepin N, Zhang J, Perbandt M, Mancuso A, Betzel C, Chapman H, Barty A
NAT COMMUN. 2018;9(1):4025.

Acting on Actin:Rac and Rho Played by Yersinia
Aepfelbacher M, Wolters M
CURR TOP MICROBIOL. 2017;399:201-220.

Emergence of ceftazidime/avibactam non-susceptibility in an MDR Klebsiella pneumoniae isolate
Both A, Büttner H, Huang J, Perbandt M, Belmar Campos C, Christner M, Maurer F, Kluge S, König C, Aepfelbacher M, Wichmann D, Rohde H
J ANTIMICROB CHEMOTH. 2017;72(9):2483-2488.

Two-tier approach combining molecular and culture-based techniques for optimized detection of vancomycin-resistant enterococci
Both A, Franke G, Mirwald N, Lütgehetmann M, Christner M, Klupp E, Belmar Campos C, Büttner H, Aepfelbacher M, Rohde H
DIAGN MICR INFEC DIS. 2017;89(4):253-257.

Molecular analysis of the ramRA locus in clinical Klebsiella pneumoniae isolates with reduced susceptibility to tigecycline
Campos C, Aepfelbacher M, Hentschke M
NEW MICROBIOL. 2017;40(2):135-138.

p38(MAPK)/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection
Menon M, Gropengießer J, Fischer J, Novikova L, Deuretzbacher A, Lafera J, Schimmeck H, Czymmeck N, Ronkina N, Kotlyarov A, Aepfelbacher M, Gaestel M, Ruckdeschel K
NAT CELL BIOL. 2017;19(10):1248-1259.

Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells
Berneking L, Schnapp M, Rumm A, Trasak C, Ruckdeschel K, Alawi M, Grundhoff A, Kikhney A, Nolte F, Buck F, Perbandt M, Betzel C, Svergun D, Hentschke M, Aepfelbacher M
PLOS PATHOG. 2016;12(6):e1005660.

First report of Escherichia coli co-producing NDM-1 and OXA-232
Both A, Huang J, Kaase M, Hezel J, Wertheimer D, Fenner I, Günther T, Grundhoff A, Büttner H, Aepfelbacher M, Rohde H, Hentschke M
DIAGN MICR INFEC DIS. 2016;86(4):437-438.

Extended spectrum beta-lactamase producing Enterobacteriaceae causing bloodstream infections in rural Ghana, 2007-2012
Eibach D, Campos C, Krumkamp R, Al-Emran H, Dekker D, Boahen K, Kreuels B, Adu-Sarkodie Y, Aepfelbacher M, Park S, Panzner U, Marks F, May J
INT J MED MICROBIOL. 2016;306(4):249-54.

Tedizolid susceptibility in linezolid- and vancomycin-resistant Enterococcus faecium isolates
Klupp E, Both A, Belmar Campos C, Büttner H, König C, Christopeit M, Christner M, Aepfelbacher M, Rohde H
EUR J CLIN MICROBIOL. 2016;35(12):1957-1961.

Staphylococcus aureus recruits Cdc42GAP through recycling endosomes and the exocyst to invade human endothelial cells
Rauch L, Hennings K, Trasak C, Röder A, Schröder B, Nolte F, Rivera-Molina F, Toomre D, Aepfelbacher M
J CELL SCI. 2016;129(15):2937-49.

Tropheryma whipplei in children with diarrhoea in rural Ghana
Vinnemeier C, Klupp E, Krumkamp R, Rolling T, Fischer N, Owusu-Dabo E, Addo M, Adu-Sarkodie Y, Käsmaier J, Aepfelbacher M, Cramer J, May J, Tannich E
CLIN MICROBIOL INFEC. 2016;22(1):65.e1 - 65.e3.

Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples
Fischer N, Indenbirken D, Meyer T, Lütgehetmann M, Lellek H, Spohn M, Aepfelbacher M, Alawi M, Grundhoff A
J CLIN MICROBIOL. 2015;53(7):2238-50.

Hepatitis E Virus
Pauli G, Aepfelbacher M, Bauerfeind U, Blümel J, Burger R, Gärtner B, Gröner A, Gürtler L, Heiden M, Hildebrandt M, Jansen B, Offergeld R, Schlenkrich U, Schottstedt V, Seitz R, Strobel J, Willkommen H, Baylis S
TRANSFUS MED HEMOTH. 2015;42(4):247-65.

Analysis of Yersinia enterocolitica Effector Translocation into Host Cells Using Beta-lactamase Effector Fusions.
Wolters M, Zobiak B, Nauth T, Aepfelbacher M
JOVE-J VIS EXP. 2015;(104):.

Prevalence and genotypes of extended spectrum beta-lactamases in Enterobacteriaceae isolated from human stool and chicken meat in Hamburg, Germany
Belmar Campos C, Fenner I, Wiese N, Lensing C, Christner M, Rohde H, Aepfelbacher M, Fenner T, Hentschke M
INT J MED MICROBIOL. 2014;304(5-6):678-684.

Rapid MALDI-TOF mass spectrometry strain typing during a large outbreak of Shiga-Toxigenic Escherichia coli
Christner M, Trusch M, Rohde H, Kwiatkowski M, Schlüter H, Wolters M, Aepfelbacher M, Hentschke M
PLOS ONE. 2014;9(7):e101924.

Rapid Metagenomic Diagnostics for Suspected Outbreak of Severe Pneumonia
Fischer N, Rohde H, Indenbirken D, Günther T, Reumann K, Lütgehetmann M, Meyer T, Kluge S, Aepfelbacher M, Alawi M, Grundhoff A
EMERG INFECT DIS. 2014;20(6):1072-5.

Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay
Meyer T, Franke G, Polywka S, Lütgehetmann M, Gbadamosi J, Magnus T, Aepfelbacher M
J CLIN MICROBIOL. 2014;52(5):1751-3.

Cell death triggered by Yersinia enterocolitica identifies processing of the proinflammatory signal adapter MyD88 as a general event in the execution of apoptosis
Novikova L, Czymmeck N, Deuretzbacher A, Buck F, Richter K, Weber A, Aepfelbacher M, Ruckdeschel K
J IMMUNOL. 2014;192(3):1209-19.

A role for exocyst in maturation and bactericidal function of staphylococci-containing endothelial cell phagosomes
Rauch L, Hennings K, Aepfelbacher M
TRAFFIC. 2014;15(10):1083-98.

Surveillanceberichte zu Erregern und Antibiotikaresistenzen - eine Empfehlung zur Standardisierung
Warnke P, Aepfelbacher M, Fickenscher H, Solbach W, Steinmetz I, Podbielski A
DEUT MED WOCHENSCHR. 2014;139(25-26):1377-82.

A culture-independent sequence-based metagenomics approach to the investigation of an outbreak of Shiga-toxigenic Escherichia coli O104:H4
Loman N, Constantinidou C, Christner M, Rohde H, Chan J, Quick J, Weir J, Quince C, Smith G, Betley J, Aepfelbacher M, Pallen M
JAMA-J AM MED ASSOC. 2013;309(14):1502-10.

Duration of fecal shedding of Shiga toxin-producing Escherichia coli O104:H4 in patients infected during the 2011 outbreak in Germany: a multicenter study
Vonberg R, Höhle M, Aepfelbacher M, Bange F, Belmar Campos C, Claussen K, Christner M, Cramer J, Haller H, Hornef M, Fickenscher H, Zimmermann-Fraedrich K, Knobloch J, Kühbacher T, Manns M, Nitschke M, Peters G, Pulz M, Rohde H, Roseland R, Sayk F, Schaumburg F, Schöcklmann H, Schubert S, Solbach W, Karch H, Suerbaum S
CLIN INFECT DIS. 2013;56(8):1132-40.

Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein
Wolters M, Boyle C, Lardong K, Trülzsch K, Steffen A, Rottner K, Ruckdeschel K, Aepfelbacher M
J BIOL CHEM. 2013;288(32):23543-53.

Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs.
Aepfelbacher M, Roppenser B, Hentschke M, Ruckdeschel K
EUR J CELL BIOL. 2011;90(11):951-954.

Destabilization of YopE by the Ubiquitin-Proteasome Pathway Fine-Tunes Yop Delivery into Host Cells and Facilitates Systemic Spread of Yersinia enterocolitica in Host Lymphoid Tissue.
Gaus K, Hentschke M, Czymmeck N, Novikova L, Trülzsch K, Valentin-Weigand P, Aepfelbacher M, Ruckdeschel K
INFECT IMMUN. 2011;79(3):1166-1175.

Emergence of carbapenemases in Gram-negative bacteria in Hamburg, Germany.
Hentschke M, Goritzka V, Belmar Campos C, Merkel P, Ilchmann C, Lellek H, Scherpe S, Aepfelbacher M, Rohde H
DIAGN MICR INFEC DIS. 2011;71(3):312-315.

CMY-42, a novel plasmid-mediated CMY-2 variant AmpC beta-lactamase.
Hentschke M, Kotsakis S, Wolters M, Heisig P, Miriagou V, Aepfelbacher M
MICROB DRUG RESIST. 2011;17(2):165-169.

Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4.
Rohde H, Qin J, Cui Y, Li D, Loman N, Hentschke M, Chen W, Pu F, Peng Y, Li J, Xi F, Li S, Li Y, Zhang Z, Yang X, Zhao M, Wang P, Guan Y, Cen Z, Zhao X, Christner M, Kobbe R, Loos S, Oh J, Yang L, Danchin A, Gao G, Song Y, Li Y, Yang H, Wang J, Xu J, Pallen M, Wang J, Aepfelbacher M, Yang R, Consortium E
NEW ENGL J MED. 2011;365(8):718-724.

Staphylococcus epidermidis uses distinct mechanisms of biofilm formation to interfere with phagocytosis and activation of mouse macrophage-like cells 774A.1.
Schommer N, Christner M, Hentschke M, Ruckdeschel K, Aepfelbacher M, Rohde H
INFECT IMMUN. 2011;79(6):2267-2276.

Organelle segregation into Plasmodium liver stage merozoites.
Stanway R, Mueller N, Zobiak B, Graewe S, Froehlke U, Zessin P, Aepfelbacher M, Heussler V
CELL MICROBIOL. 2011;13(11):1768-1782.

MALDI-TOF MS fingerprinting allows for discrimination of major methicillin-resistant Staphylococcus aureus lineages.
Wolters M, Rohde H, Maier T, Belmar Campos C, Franke G, Scherpe S, Aepfelbacher M, Christner M
INT J MED MICROBIOL. 2011;301(1):64-68.

Diagnosis of Toxoplasma gondii infection after allogeneic stem cell transplant can be difficult and requires intensive scrutiny.
Cavattoni I, Ayuketang Ayuk F, Zander A, Zabelina T, Bacher A, Cayiroglu E, Knospe V, Illies T, Aepfelbacher M, Richard G, Kröger N, Bacher U
LEUKEMIA LYMPHOMA. 2010;51(8):1530-1535.

The giant extracellular matrix-binding protein of Staphylococcus epidermidis mediates biofilm accumulation and attachment to fibronectin.
Christner M, Franke G, Schommer N, Wendt U, Wegert K, Pehle P, Kroll G, Schulze C, Buck F, Mack D, Aepfelbacher M, Rohde H
MOL MICROBIOL. 2010;75(1):187-207.

Rapid identification of bacteria from positive blood culture bottles by use of matrix-assisted laser desorption-ionization time of flight mass spectrometry fingerprinting.
Christner M, Rohde H, Wolters M, Sobottka I, Wegscheider K, Aepfelbacher M
J CLIN MICROBIOL. 2010;48(5):1584-1591.

Xenotropic murine leukemia virus-related gammaretrovirus in respiratory tract.
Fischer N, Schulz C, Stieler K, Hohn O, Lange C, Drosten C, Aepfelbacher M
EMERG INFECT DIS. 2010;16(6):1000-1002.

Epidemiology, variable genetic organisation and regulation of the EDIN-B toxin in Staphylococcus aureus from bacteraemic patients.
Franke G, Böckenholt A, Sugai M, Rohde H, Aepfelbacher M
MICROBIOL-SGM. 2010;156:860-872.

Yersinia virulence factor YopM induces sustained RSK activation by interfering with dephosphorylation.
Hentschke M, Berneking L, Campos C, Buck F, Ruckdeschel K, Aepfelbacher M
PLOS ONE. 2010;5(10):.

ramR mutations in clinical isolates of Klebsiella pneumoniae with reduced susceptibility to tigecycline.
Hentschke M, Wolters M, Sobottka I, Rohde H, Aepfelbacher M
ANTIMICROB AGENTS CH. 2010;54(6):2720-2723.

Host range and cellular tropism of the human exogenous gammaretrovirus XMRV.
Stieler K, Schulz C, Lavanya M, Aepfelbacher M, Stocking C, Fischer N
VIROLOGY. 2010;399(1):23-30.

Beta1 integrin-dependent engulfment of Yersinia enterocolitica by macrophages is coupled to the activation of autophagy and suppressed by type III protein secretion.
Deuretzbacher A, Czymmeck N, Reimer R, Trülzsch K, Gaus K, Hohenberg H, Heesemann J, Aepfelbacher M, Ruckdeschel K
J IMMUNOL. 2009;183(9):5847-5860.

Combined ramR mutation and presence of a Tn1721-associated tet(A) variant in a clinical isolate of Salmonella enterica Serovar Hadar resistant to Tigecycline.
Hentschke M, Christner M, Sobottka I, Aepfelbacher M, Rohde H
ANTIMICROB AGENTS CH. 2009.

Yersinia enterocolitica differentially modulates RhoG activity in host cells.
Roppenser B, Röder A, Hentschke M, Ruckdeschel K, Aepfelbacher M
J CELL SCI. 2009;122(5):696-705.

GFP-targeting allows visualization of the apicoplast throughout the life cycle of live malaria parasites.
Stanway R, Witt T, Zobiak B, Aepfelbacher M, Heussler V
BIOL CELL. 2009;101(7):415-430, 430.

Alteration of the parasite plasma membrane and the parasitophorous vacuole membrane during exo-erythrocytic development of malaria parasites.
Sturm A, Graewe S, Franke-Fayard B, Retzlaff S, Bolte S, Roppenser B, Aepfelbacher M, Janse C, Heussler V
PROTIST. 2009;160(1):51-63.

Prevalence of human gammaretrovirus XMRV in sporadic prostate cancer.
Fischer N, Hellwinkel O, Schulz C, Chun F, Huland H, Aepfelbacher M, Schlomm T
J CLIN VIROL. 2008;43(3):277-283.

Emergence of linezolid resistance in a methicillin resistant Staphylococcus aureus strain.
Hentschke M, Saager B, Horstkotte M, Scherpe S, Wolters M, Kabisch H, Grosse R, Heisig P, Aepfelbacher M, Rohde H
INFECTION. 2008;36(1):85-87.

Regulation of epidermal tight-junctions (TJ) during infection with exfoliative toxin-negative Staphylococcus strains.
Ohnemus U, Kohrmeyer K, Houdek P, Rohde H, Wladykowski E, Vidal S, Horstkotte M, Aepfelbacher M, Kirschner N, Behne M, Moll I, Brandner J
J INVEST DERMATOL. 2008;128(4):906-916.

Effector functions of pathogenic Yersinia species.
Aepfelbacher M, Trasak C, Ruckdeschel K
THROMB HAEMOSTASIS. 2007;98(3):521-529.

Expression and functional characterization of gfpmut3.1 and its unstable variants in Staphylococcus epidermidis.
Franke G, Dobinsky S, Mack D, Wang C, Sobottka I, Christner M, Knobloch J, Horstkotte M, Aepfelbacher M, Rohde H
J MICROBIOL METH. 2007;71(2):123-132.

Lactobacillus fermentum attenuates the proinflammatory effect of Yersinia enterocolitica on human epithelial cells.
Frick J, Schenk K, Quitadamo M, Kahl F, Köberle M, Bohn E, Aepfelbacher M, Autenrieth I
INFLAMM BOWEL DIS. 2007;13(1):83-90.

Serogroup-related escape of Yersinia enterocolitica YopE from degradation by the ubiquitin-proteasome pathway.
Hentschke M, Trülzsch K, Heesemann J, Aepfelbacher M, Ruckdeschel K
INFECT IMMUN. 2007;75(9):4423-4431.

Yersinia protein kinase YopO is activated by a novel G-actin binding process.
Trasak C, Zenner G, Vogel A, Yüksekdag G, Rost R, Haase I, Fischer M, Israel L, Imhof A, Linder S, Schleicher M, Aepfelbacher M
J BIOL CHEM. 2007;282(4):2268-2277.

Micromechanics of filopodia mediated capture of pathogens by macrophages.
Vonna L, Wiedemann A, Aepfelbacher M, Sackmann E
EUR BIOPHYS J BIOPHY. 2007;36(2):145-151.

The kinesin KIF1C and microtubule plus ends regulate podosome dynamics in macrophages.
Kopp P, Lammers R, Aepfelbacher M, Woehlke G, Rudel T, Machuy N, Steffen W, Linder S
MOL BIOL CELL. 2006;17(6):2811-2823.

The proteasome pathway destabilizes Yersinia outer protein E and represses its antihost cell activities.
Ruckdeschel K, Pfaffinger G, Trülzsch K, Zenner G, Richter K, Heesemann J, Aepfelbacher M
J IMMUNOL. 2006;176(10):6093-6102.

Live cell imaging of phagosome maturation in Staphylococcus aureus infected human endothelial cells: small colony variants are able to survive in lysosomes.
Schröder A, Kland R, Peschel A, von Eiff C, Aepfelbacher M
MED MICROBIOL IMMUN. 2006;195(4):185-194.

Staphylococcus aureus fibronectin binding protein-A induces motile attachment sites and complex actin remodeling in living endothelial cells.
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